Antigenotoxic and Life-Prolonging Effects of Flavoured Kombuchas on Drosophila melanogaster


Burgazlı A. Y., Tagorti G., Yalçın B., Güneş M., Eroğlu B., Delik E., ...Daha Fazla

Food Technology and Biotechnology, cilt.62, sa.2, ss.133-139, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.17113/ftb.62.02.24.8308
  • Dergi Adı: Food Technology and Biotechnology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, Business Source Elite, Business Source Premier, CAB Abstracts, Central & Eastern European Academic Source (CEEAS), Compendex, Environment Index, Food Science & Technology Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.133-139
  • Anahtar Kelimeler: antigenotoxicity, Drosophila melanogaster, kombucha, lifespan
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Research background. Kombucha is a fermented beverage with several health benefits; however, to improve its antioxidant activity, new raw materials such as hop, madimak and hawthorn were included in the present study. Experimental approach. The somatic mutation and recombination test (SMART) was performed on the fruit fly (Drosophila melanogaster) to evaluate the antigenotoxic potential of black tea-flavoured kombucha and three other flavours of kombuchas (hop, madi-mak and hawthorn) against H2O2-and K2Cr2O7-induced genotoxicity. Furthermore, a lifespan assay was performed to assess the effects of kombuchas on the longevity of the fruit fly. Results and conclusions. According to the results obtained from the SMART assay, hop--flavoured kombucha attenuated genotoxicity induced by H2O2, and madimak-flavoured kombucha reduced genotoxicity induced by H2O2 and K2Cr2O7. Black tea-and hop-fla-voured kombucha prolonged the lifespan of the fruit fly (Drosophila melanogaster) after the treatment with H2O2 and K2Cr2O7. Novelty and scientific contribution. Hop-flavoured kombucha is a promising antioxidant that protects the genome and extends the lifespan of the fruit fly. This study sheds light on novel beverages that can combat ageing and protect against genotoxicity.