TAFRO syndrome treated effectively with corticosteroids: A case report and review of the literature

SÖZEL H., AVŞAR E.

Indian Journal of Nephrology, cilt.32, sa.2, ss.168-171, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 32 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4103/ijn.ijn-520-20
  • Dergi Adı: Indian Journal of Nephrology
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.168-171
  • Anahtar Kelimeler: Castleman's disease, corticosteroid treatment, TAFRO syndrome
  • Akdeniz Üniversitesi Adresli: Evet

Özet

© 2022 Wolters Kluwer Medknow Publications. All rights reserved.TAFRO (thrombocytopenia, anasarca, fever, renal dysfunction, and organomegaly) syndrome is a subtype of Castleman's disease and has been described in recent years. In this case, a middle-aged woman was admitted to our clinic with a 2-week history of fever, weakness, cough, shortness of breath and edema all over the body. Physical examination on admission revealed pale conjunctiva, tachycardia, coarse crackles over left lower lung fields, pitting edema in the extremities, tense ascites, axillar, and bilateral inguinal lymph nodes measuring less than 2 cm. Inguinal lymph node excisional biopsy was compatible with TAFRO syndrome. We started corticosteroid treatment. The patient's general condition and physical findings improved. Laboratory values returned to normal limits. This case will help understand the clinical course and treatment strategy in TAFRO syndrome.