Serum N-Desmethylcitalopram Concentrations are Associated with the Clinical Response to Citalopram of Patients with Major Depression

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ÖZBEY G., Yücel B., BODUR N. E., TAYCAN S. E., ARSLAN T., CERIT N., ...Daha Fazla

PSYCHIATRY INVESTIGATION, cilt.15, sa.3, ss.313-319, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.30773/pi.2017.05.22
  • Dergi Adı: PSYCHIATRY INVESTIGATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.313-319
  • Anahtar Kelimeler: Serum concentration, Citalopram, N-desmethylcitalopram, Efficacy, Tolerability, Major depression, ANTIDEPRESSANT DRUGS, METABOLITES, POPULATION, PSYCHIATRY, INHIBITORS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective Citalopram (CITA) is a widely used and well-tolerated selective serotonin reuptake inhibitor. The aim of the study was to evaluate the possible influences of serum concentrations of CITA and its major metabolite n-desmethylcitalopram (NDCITA) on the efficacy and tolerability of CITA in patients with major depressive disorder.