Serum N-Desmethylcitalopram Concentrations are Associated with the Clinical Response to Citalopram of Patients with Major Depression


Creative Commons License

ÖZBEY G., Yücel B., BODUR N. E., TAYCAN S. E., ARSLAN T., CERIT N., ...More

PSYCHIATRY INVESTIGATION, vol.15, no.3, pp.313-319, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.30773/pi.2017.05.22
  • Journal Name: PSYCHIATRY INVESTIGATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.313-319
  • Keywords: Serum concentration, Citalopram, N-desmethylcitalopram, Efficacy, Tolerability, Major depression, ANTIDEPRESSANT DRUGS, METABOLITES, POPULATION, PSYCHIATRY, INHIBITORS
  • Akdeniz University Affiliated: Yes

Abstract

Objective Citalopram (CITA) is a widely used and well-tolerated selective serotonin reuptake inhibitor. The aim of the study was to evaluate the possible influences of serum concentrations of CITA and its major metabolite n-desmethylcitalopram (NDCITA) on the efficacy and tolerability of CITA in patients with major depressive disorder.