Journal of Clinical Anesthesiology Research, 2021 (Hakemli Dergi)
Propofol is an anesthetic agent commonly used for sedation and induction and/or maintenance of general
anesthesia and presents an inhibitory effect on the excitatory neurotransmitters through GABA receptors. Although
propofol is an agent that can be used to treat status epilepticus because of its anticonvulsant property, it may
cause epileptiform convulsions, as reported in the literature. In this case report, a young patient’s epileptiform
convulsions after administering a single dose of propofol injection for general anesthesia are presented. Due to
uncontrolled epilepsy episodes following extubation, the patient was taken to intensive care. The patient regained
consciousness, and epileptic attacks were controlled on the 4th day of intensive, was taken to the neurology
service. We consider that this case is noteworthy concerning the association between propofol and epilepsy in
anesthesia. Thus, this study aimed to draw attention to propofol in patients with a history of epilepsy.