Unified definition of integrated diagnostics: a position statement of the EFLM


Lennerz J. K., Del Ben F., Stenzinger A., Frauenknecht K. B., Carobene A., Berishvili N., ...More

Clinical Chemistry and Laboratory Medicine, 2026 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Publication Date: 2026
  • Doi Number: 10.1515/cclm-2026-0949
  • Journal Name: Clinical Chemistry and Laboratory Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
  • Keywords: biomarker, définition, inegrated diagnostics, radiology
  • Akdeniz University Affiliated: Yes

Abstract

Integrated diagnostics is an emerging multidisciplinary model of care that integrates traditionally siloed domains, including pathology, radiology, genomics, and laboratory medicine, into a coordinated framework designed to improve diagnostic accuracy, treatment selection, and clinical outcomes. In this position statement, the EFLM Integrated Diagnostics Committee proposes a concise and operational definition of integrated diagnostics and outlines the relevance for healthcare systems. Integrated diagnostics has the potential to advance precision medicine through improved data integration, more coordinated interpretation, and enhanced clinical decision-making. Drawing on multidisciplinary expert consensus, we recommend adoption of a standardized conceptual framework to support research, clinical implementation, interoperability, and policy development across healthcare systems with implementation adapted to local needs, scale, and digital maturity.