Topical granulocyte colony-stimulating factor for the treatment of oral and genital ulcers of patients with Behcet's disease

Bacanli, A.; Dicle, ÖZLEM; Parmaksizoglu, B.; Yilmaz, ERTAN; Alpsoy, ERKAN

doi:10.1111/j.1468-3083.2006.01677.x

Topical granulocyte colony-stimulating factor for the treatment of oral and genital ulcers of patients with Behcet's disease

Bacanli A., Dicle O. Y., Parmaksizoglu B., Yilmaz E., Alpsoy E.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, vol.20, no.8, pp.931-935, 2006 (SCI-Expanded)

Publication Type: Article / Article
Volume: 20 Issue: 8
Publication Date: 2006
Doi Number: 10.1111/j.1468-3083.2006.01677.x
Journal Name: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.931-935
Keywords: Behcet's disease, G-CSF, genital ulcers, oral ulcers, therapy, topical, IN-VITRO, CYTOKINE DRESSINGS, RHGM-CSF
Akdeniz University Affiliated: Yes

Abstract

Background Recurrent and painful ulcers of the oral mucosa and genital skin/mucosa are the most commonly observed manifestations in patients with Behcet's disease (BD). They affect patients' quality of life. Because of the effectiveness of granulocyte colony-stimulating factor (G-CSF) in wound healing, it may also be useful for the treatment of oral ulcers (OU) and genital ulcers (GU) of BD.