İzmir Göğüs Hastalıkları Dergisi, cilt.111, ss.111, 2020 (Hakemli Dergi)
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Tracheobronchopatia osteochondroplastica (TPO) is characterized by cartilagious and osseous nodules in the trachea and bronchi. The estimated prevalence is about 0.1%. It is rather seen in adulthood. Although it is thought to be more common in men, gender preference is not clear. It is suggested that the nodules develop as a result of exocytosis and enchondrosis originating from cartilage rings but the exact pathogenesis is unknown. As an etiology comorbid conditions such as infections, atrophic rhinitis and pneumoconiosis are blamed in some cases but the exact etiology is not known either. Most of the TPO cases are asymptomatic and are diagnosed incidentally. In symptomatic TPO, the most common symptoms are chronic cough and dyspnea. The diagnosis can be made based on radiological findings alone. Fiberoptic bronchoscopy can be performed to confirm the diagnosis and rule out other causes such as endobronchial sarcoidosis, amyloidosis, relapsing polychondritis, papilllamosis, tracheal calcinosis, carcinoma. In cases of TPO, treatment is rarely required. For symptom palliation, inhaler bronchodilator, inhaler steroid, nonsteroidal anti-inflammatory drugs, dapsone, which are reported to be effective in some cases, can be used. In patients with severe airway stenosis, more invasive procedures such as bronchoscopic laser ablation, argon plasma coagulation / cryotherapy, stent, surgical resection can be performed. Here, an asymptomatic prosiasis TPO case, diagnosed insidentally during an acute respiratory infection is presented with the literature review.