Light-activated hybrid organic/inorganic antimicrobial coatings

AKARSU E., Uslu R.

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, cilt.87, sa.1, ss.183-194, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 87 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s10971-018-4714-y
  • Dergi Adı: JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.183-194
  • Anahtar Kelimeler: Antimicrobial, Hybrid coating, Photo-sensitizer, Sol-gel, ROSE-BENGAL, METHYLENE-BLUE, PHOTOSENSITIZERS, INFECTIONS, PROTEINS, SURFACES, BACTERIA, DESIGN, IMPACT, COSTS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Light-activated antimicrobial coatings were obtained by the covalently immobilizing photo-sensitizers in a hybrid organic/inorganic matrix. These coatings were deposited via sol-gel chemistry using epoxy and methyl functional silanes. The light-activated chromophores used in this study were Methylene Blue, Toluidine Blue O, and Rose Bengal. The immobilized photo-sensitizers did not leach from the coatings. The mechanically durable hybrid coatings comprising 2.5% by weight of Rose Bengal had a good adhesion to the glass surface. These coatings were tested for the photo-deactivation of Escherichia coli and Staphylococcus aureus using illumination by a commercial fluorescent lamp. Log reduction of E. coli and S. aureus were > 4 when illuminated by the fluorescent lamp in 1 and 3 h, respectively. Due to its high mechanical durability and chemical resistance, such light-activated hybrid coatings are promising candidates for indoor applications in healthcare facilities.