Association of paraoxonase activity and coronary blood flow
ATHEROSCLEROSIS, vol.197, no.1, pp.257-263, 2008 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 197 Issue: 1
- Publication Date: 2008
- Doi Number: 10.1016/j.atherosclerosis.2007.04.004
- Journal Name: ATHEROSCLEROSIS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.257-263
- Keywords: paraoxonase, coronary blood flow, slow coronary flow, atherosclerosis, endothelial dysfunction, LOW-DENSITY-LIPOPROTEIN, SERUM PARAOXONASE, ENDOTHELIAL FUNCTION, GENE POLYMORPHISMS, ARTERY-DISEASE, HEART-DISEASE, NITRIC-OXIDE, Q192R POLYMORPHISM, FRAME COUNT, PON1 GENE
- Akdeniz University Affiliated: No
Abstract
Background: Paraoxonase (PON) is a high-density lipoprotein-bound anti-oxidant enzyme that inhibits atherosclerosis and endothelial dysfunction. Slow coronary flow (SCF) has long been identified and endothelial dysfunction and atherosclerosis of epicardial coronary arteries and microvasculature were reported to be associated with SCE Consequently, we aimed to investigate the association between coronary blood flow by means of Thrombolysis in Myocardial Infarction frame count (TFC) and serum PON activity and other laboratory parameters in patients with SCF compared to control cases.