Association of paraoxonase activity and coronary blood flow

Yildiz A., Gur M., Yilmaz R., Demirbag R., Polat M., SELEK Ş., ...Daha Fazla

ATHEROSCLEROSIS, cilt.197, sa.1, ss.257-263, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 197 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.atherosclerosis.2007.04.004
  • Dergi Adı: ATHEROSCLEROSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.257-263
  • Anahtar Kelimeler: paraoxonase, coronary blood flow, slow coronary flow, atherosclerosis, endothelial dysfunction, LOW-DENSITY-LIPOPROTEIN, SERUM PARAOXONASE, ENDOTHELIAL FUNCTION, GENE POLYMORPHISMS, ARTERY-DISEASE, HEART-DISEASE, NITRIC-OXIDE, Q192R POLYMORPHISM, FRAME COUNT, PON1 GENE
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Background: Paraoxonase (PON) is a high-density lipoprotein-bound anti-oxidant enzyme that inhibits atherosclerosis and endothelial dysfunction. Slow coronary flow (SCF) has long been identified and endothelial dysfunction and atherosclerosis of epicardial coronary arteries and microvasculature were reported to be associated with SCE Consequently, we aimed to investigate the association between coronary blood flow by means of Thrombolysis in Myocardial Infarction frame count (TFC) and serum PON activity and other laboratory parameters in patients with SCF compared to control cases.