Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, bovine citrullinaemia and factor XI deficiency in Holstein cattle

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KAYA M., Meydan H., KIYMA Z., ALAN M., YILDIZ M.

INDIAN JOURNAL OF ANIMAL SCIENCES, cilt.86, sa.8, ss.900-903, 2016 (SCI-Expanded)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 86 Sayı: 8
  • Basım Tarihi: 2016
  • Dergi Adı: INDIAN JOURNAL OF ANIMAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.900-903
  • Anahtar Kelimeler: BC, BLAD, DUMPS, FXID, Holstein cattle, PCR-RFLP, COMPLEX VERTEBRAL MALFORMATION, BLAD, IDENTIFICATION, CARRIERS, DUMPS, MUTATION, COWS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Holstein cattle reared in Eskisehir region were monitored with respect to the genetic disorders defined as bovine leukocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase (DUMPS), bovine citrullinaemia (BC) and factor XI deficiency (FXID). To determine the presence of BLAD, DUMPS, BC and FXID genotypes, Holstein cattle (219) were sampled. Three BLAD and 2 FXID carriers were identified among the 219 Holstein cattle examined, while none of the cows carried DUMPS and BC. Current study demonstrated that carriers of BLAD and FXID are present in the Turkish Holstein population in Eskisehir region, although at a low frequency. Since, artificial insemination is widely used in these populations, determination of the carriers of hereditary disorders within the population of breeding sires has become essential. To prevent economic losses resulting from genetic disorders, it is advised to screen breeding sires for these genotypes. The aim of this study was to investigate existence and prevalence of BLAD, DUMPS, BC and FXID alleles in Holstein cattle reared in Eskisehir region by using PCR and PCR-RFLP methods.

Holstein cattle reared in Eskisehir region were monitored with respect to the genetic disorders defined as bovine
leukocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase (DUMPS), bovine
citrullinaemia (BC) and factor XI deficiency (FXID). To determine the presence of BLAD, DUMPS, BC and FXID
genotypes, Holstein cattle (219) were sampled. Three BLAD and 2 FXID carriers were identified among the 219
Holstein cattle examined, while none of the cows carried DUMPS and BC. Current study demonstrated that carriers
of BLAD and FXID are present in the Turkish Holstein population in Eskisehir region, although at a low frequency.
Since, artificial insemination is widely used in these populations, determination of the carriers of hereditary disorders
within the population of breeding sires has become essential. To prevent economic losses resulting from genetic
disorders, it is advised to screen breeding sires for these genotypes. The aim of this study was to investigate
existence and prevalence of BLAD, DUMPS, BC and FXID alleles in Holstein cattle reared in Eskisehir region by
using PCR and PCR-RFLP methods.