The Dialysis Outcomes and Practice Patterns Study (DOPPS) in Turkey

Ecder T., Utas C., ATEŞ K., Bieber B., Robinson B. M., Pisoni R. L., ...More

HEMODIALYSIS INTERNATIONAL, vol.21, no.3, pp.430-439, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1111/hdi.12504
  • Journal Name: HEMODIALYSIS INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.430-439
  • Keywords: Chronic hemodialysis, chronic renal failure, dialysis, end-stage renal disease, hemodialysis, CHRONIC KIDNEY-DISEASE, VASCULAR ACCESS USE, QUALITY-OF-LIFE, SECONDARY HYPERPARATHYROIDISM, PSYCHOSOCIAL FACTORS, PRACTICE MONITOR, HEMODIALYSIS, MORTALITY, ANEMIA, HOSPITALIZATION
  • Akdeniz University Affiliated: Yes

Abstract

Introduction: Turkey has one of the largest treated end-stage renal disease (ESRD) patient populations in Europe (N=66,711). In 2013, the international Dialysis Outcomes and Practice Patterns Study (DOPPS), a prospective study of hemodialysis (HD) practices and outcomes, initiated data collection in Turkey. Here we provide comparisons of HD patients in DOPPS-Turkey with other international regions and with patients in the Registry of Turkish Nephrology, Dialysis and Transplantation. Methods: DOPPS-Turkey study sites were randomly selected from all Turkish HD units treating 25 in-center chronic HD patients. Detailed patient- and facility-level data were collected for 20-30 randomly selected prevalent HD patients per facility. Findings: Demographic and comorbidity profiles for DOPPS-Turkey patients were similar to HD patients overall in the 2013 Turkish Registry Report. In Turkey: diabetes was the most common ESRD cause (37%); arteriovenous fistula use was 83%; mean single pool Kt/V was 1.61. Compared with other international regions, Turkey had the highest mean hemoglobin (11.5 g/dL), ferritin (771 ng/mL), and interdialytic weight gain (3.28%), while Turkey had the lowest mean systolic blood pressure (127 mmHg) and erythropoiesis stimulating agent prescription (57%). Turkish patients also reported the highest depression scores. Discussion: In this first DOPPS-Turkey report, the DOPPS sample agrees well with national Turkish Registry data. Treatment and laboratory data, and patient-reported outcomes, demonstrate similarities and previously unrecognized contrasts to DOPPS findings in Europe, Japan, and North America. Long-term follow-up of these patients will describe how these differences relate to clinical outcomes within Turkey.