Single Optical Fiber Probe Spectroscopy for Detection of Dysplastic Tissues
22nd International Conference on Nonlinear Dynamics of Electronic Systems (NDES), Albena, Bulgaristan, 4 - 06 Temmuz 2014, cilt.438, ss.349-354, (Tam Metin Bildiri)
- Yayın Türü: Bildiri / Tam Metin Bildiri
- Cilt numarası: 438
- Doi Numarası: 10.1007/978-3-319-08672-9_41
- Basıldığı Şehir: Albena
- Basıldığı Ülke: Bulgaristan
- Sayfa Sayıları: ss.349-354
- Anahtar Kelimeler: Single-scattering spectroscopy, Cancer, Diagnosis, Non-invasive, Real-time, SCATTERING SPECTROSCOPY, LIGHT-SCATTERING, CELLS
- Akdeniz Üniversitesi Adresli: Evet
Özet
A single optical fiber probe with a core diameter of 100 mu m was used to deliver visible light to tissue and from tissue to a spectrometer to diagnose cancerous tissues of different organs. Measurements were performed on brain, skin, cervix and prostate tumor specimens and surrounding normal tissues ex-vivo. The spectral slopes were positive for normal tissues and negative for the tumors. Signs of the spectral slopes were used as a discrimination parameter to differentiate tumor from normal tissues for the four organ tissues. Sensitivity and specificity of the system in differentiation between tumors from normal tissues were 93% and % 100 for brain, 87% and 85% for skin, 93.7% and 46.1% for cervix and 98% and 100% for prostate respectively.