Akademik Veri Yönetim Sistemi
16. World Congress of anaesthesiologists, Victoria-City, Hong Kong, 28 Ağustos - 02 Eylül 2016, ss.1
Background & Objectives: There are many studies that explained the triggered role of inflammation in several disesases.
Neutrophil/lymphocyte ratio is a newly recognized marker of inflammation and certain pathological processes are found in
relation with increased NLR. In this study we aimed to investigate prognostic value of NLR in patients admitted to our
intensive care unit (ICU)
Materials & Methods: We retrospectively investigated medical records of 180 patients admitted to ICU with different
diagnosis. NLR of patients, diagnoses, prognosis and mortality rates were recorded. Demographic, clinic data, treatment
reports, complete blood count results include white blood cell count, hemoglobine, hematocrit levels and mean platelet
volume were evaluated. Also Omega and APACHE 2 scores were calculated.
Results: We retrospectively investigated medical records of 180 patients. Ninety one patients (%50.6) were female while
89 were male (%49.6). Mean age of patients was 50±23 and mean duration of admission was 7,7±15 days. Mortality rate
was %28.9 (52 patients).
There was no NLR difference between gender while increased age and admission length were associated with increased
NLR (p:0.4, p:0.01 and p:0.001 respectively).
Hypertension, sepsis, septic shock, pneumonia and COPD were positively correlated with higher NLR (p:0.01, p:0,05,
p:0,02, p:0,0001 and p:0,01). However there was no statistically significant correlation between NLR and myocard
infarctus, congestive heart failure, atrial/ventricular fibrillation, neurological events, other cardiac and endocrinologic
diseases.
Increased NLR was significantly associated only with increased Omega 3 and Apache 2 scores (p:0,01, p:0,001). Finally
we couldn’t find any significant association between mortality and NLR
Conclusion: NLR is an useful marker in several diseases which inflammation plays important role however NLR alone is
unadequate to estimate mortality. There is need for prospective, controlled studies that explain possible relationship
between NLR and progression of certain clinical diseases treated in ICU.