Tranexamic Acid and Hyaluronate/Carboxymethylcellulose Create Cell Injury
JSLS-JOURNAL OF THE SOCIETY OF LAPAROENDOSCOPIC SURGEONS, vol.18, no.3, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 18 Issue: 3
- Publication Date: 2014
- Doi Number: 10.4293/jsls.2014.00044
- Journal Name: JSLS-JOURNAL OF THE SOCIETY OF LAPAROENDOSCOPIC SURGEONS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Keywords: Adhesion, Hyaluronate/carboxymethylcellulose, Rat, Tranexamic acid, Uterine horn, POSTOPERATIVE ADHESION FORMATION, UTERINE HORN MODEL, RAT MODEL, PREVENTION, REDUCTION, MELATONIN, PRODUCT
- Open Archive Collection: AVESIS Open Access Collection
- Akdeniz University Affiliated: No
Abstract
Background and Objectives: Postoperative pelvic adhesions are associated with chronic pelvic pain, dyspareunia, and infertility. The aim of this study was to evaluate the adhesion prevention effects of tranexamic acid (TA) and hyaluronate/carboxymethylcellulose (HA/CMC) barrier in the rat uterine horn models on the basis of macroscopic and microscopic adhesion scores and histopathological as well as biochemical parameters of inflammation.