Altered Heart Rhythm Dynamics in Very Low Birth Weight Infants With Impending Intraventricular Hemorrhage

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Tuzcu V., Nas S., Ulusar U., Ugur A., Kaiser J. R.

PEDIATRICS, vol.123, no.3, pp.810-815, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 123 Issue: 3
  • Publication Date: 2009
  • Doi Number: 10.1542/peds.2008-0253
  • Journal Name: PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.810-815
  • Keywords: intraventricular hemorrhage, prematurity, very low birth weight infants, heart rate variability fractal analysis, detrended fluctuation analysis, CEREBRAL-BLOOD-FLOW, RATE-VARIABILITY, ULTRASOUND ABNORMALITIES, PARASYMPATHETIC NERVES, INDOMETHACIN, TERM, AUTOREGULATION, MORTALITY, PALSY
  • Akdeniz University Affiliated: No

Abstract

OBJECTIVE. Intraventricular hemorrhage remains an important problem among very low birth weight infants and may result in long-term neurodevelopmental disabilities. Neonatologists have been unable to accurately predict impending intraventricular hemorrhage. Because alterations in the autonomic nervous system's control of heart rhythm have been associated with intraventricular hemorrhage after its development, we sought to determine if early subtle alterations of heart rhythm could be predictive of impending intraventricular hemorrhage in very low birth weight infants.