Inhibition of mammalian target of rapamycin signaling pathway decreases retinoic acid stimulated gene 8 expression in adult mouse testis

Sahin, PINAR; Sahin, Zeliha; GUNGOR-ORDUERI, N.; Donmez, BARIŞ; Celik-Ozenci, ÇİLER

doi:10.1016/j.fertnstert.2014.08.004

Inhibition of mammalian target of rapamycin signaling pathway decreases retinoic acid stimulated gene 8 expression in adult mouse testis

Sahin P., Sahin Z., GUNGOR-ORDUERI N. E., Donmez B. Ö., Celik-Ozenci C.

FERTILITY AND STERILITY, cilt.102, sa.5, 2014 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 102 Sayı: 5
Basım Tarihi: 2014
Doi Numarası: 10.1016/j.fertnstert.2014.08.004
Dergi Adı: FERTILITY AND STERILITY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: mTOR, rapamycin, seminiferous tubule culture, STRA8, MEIOTIC INITIATION, GONADAL-FUNCTION, S6 KINASE, SIROLIMUS, TRANSLATION, EVEROLIMUS, STRA8, MTOR
Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: To evaluate the expression of mammalian target of rapamycin (mTOR) pathway molecules in mouse spermatogenesis and as well as its role during proliferation and meiotic initiation of spermatogenic cells.