Inhibition of mammalian target of rapamycin signaling pathway decreases retinoic acid stimulated gene 8 expression in adult mouse testis


Sahin P., Sahin Z., GUNGOR-ORDUERI N. E., Donmez B. Ö., Celik-Ozenci C.

FERTILITY AND STERILITY, vol.102, no.5, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 102 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.1016/j.fertnstert.2014.08.004
  • Journal Name: FERTILITY AND STERILITY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: mTOR, rapamycin, seminiferous tubule culture, STRA8, MEIOTIC INITIATION, GONADAL-FUNCTION, S6 KINASE, SIROLIMUS, TRANSLATION, EVEROLIMUS, STRA8, MTOR
  • Akdeniz University Affiliated: Yes

Abstract

Objective: To evaluate the expression of mammalian target of rapamycin (mTOR) pathway molecules in mouse spermatogenesis and as well as its role during proliferation and meiotic initiation of spermatogenic cells.