TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.29, sa.5, ss.1267-1272, 2009 (SCI-Expanded)
Objective: We aimed to investigate the effect of thiocolchicoside, a drug never used in piriformis syndrome (PS) treatment before and to compare these effects with triamcinolone, that has been used in the routine treatment for PS. Material and Methods: Our study was designed as a randomized and multicentral study in 60 patients where group I (n = 30) received triamsinolon and group II (n = 30) received thiocolchicoside. The pressure values of the trigger points were measured with an algometer at baseline, and at I month and 3 months after the procedure. The subjective complaints of the patients were evaluated with visual analog scale (VAS). Results: The demographical data and their evaluations at baseline were similar. In all groups, the trigger point pressure values were significantly higher (p = 0.019) and VAS values were significantly lower (p = 0.001) when compared to baseline values. While this significant decrease in VAS values continued in group I at 3 months, no such difference was observed in group II. Conclusion: In conclusion, triamcinolone has a similar effect compared to thiocolchicoside at one month following the administration, but the effect of triamsinolon continues at 3 months also. Thus, triamcinolone is more effective than thiocolchicoside in one-dose-shot-treatments in PS patients. Nevertheless, thiocolchicoside is still an alternative for the treatment in PS patients where triamcinolone cannot be used.