Incidental Finding of Colon Carcinoma Related to High Uptake in F-18-PSMA-1007 PET

Arcay A., Eiber M., Langbein T.

CLINICAL NUCLEAR MEDICINE, cilt.45, sa.7, ss.561-562, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 45 Sayı: 7
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1097/rlu.0000000000003081
  • Dergi Adı: CLINICAL NUCLEAR MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.561-562
  • Anahtar Kelimeler: colon carcinoma, PSMA, PET, CT, F-18-PSMA PET, CT, F-18-PSMA-1007, PSMA EXPRESSION
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

We present a 78-year-old man with suspicion of prostate cancer due to a PSA of 200 ng/mL, who underwent(18)F-PSMA-1007 (prostate specific membrane antigen) PET/CT for primary staging. Besides heterogeneous uptake to the prostate, an increased PSMA uptake in the cecum was observed, located in the thickened cecal wall with suspicion of a secondary malignancy. Colonoscopic biopsy followed by hemicolectomy confirmed the diagnosis of colon adenocarcinoma. This case demonstrates the importance of bioptic workup of suspicious findings on PSMA PET/CT, which are unlikely to be related to prostate cancer as PSMA ligand uptake is not exclusively prostate cancer specific.