Prevalence and distribution of iron overload in patients with transfusion-dependent anemias differs across geographic regions: results from the CORDELIA study

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AYDINOK Y., Porter J. B., Piga A., Elalfy M., El-Beshlawy A., KILINÇ Y., ...More

EUROPEAN JOURNAL OF HAEMATOLOGY, vol.95, no.3, pp.244-253, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 95 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1111/ejh.12487
  • Journal Name: EUROPEAN JOURNAL OF HAEMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.244-253
  • Keywords: thalassemia, heart, liver, iron, prevalence, distribution, BETA-THALASSEMIA MAJOR, T2-ASTERISK-CARDIOVASCULAR MAGNETIC-RESONANCE, RANDOMIZED CONTROLLED-TRIAL, MYOCARDIAL IRON, LIVER IRON, DEFEROXAMINE, DEFERASIROX, DEFERIPRONE, SURVIVAL, CARDIOMYOPATHY
  • Akdeniz University Affiliated: Yes

Abstract

ObjectivesThe randomized comparison of deferasirox to deferoxamine for myocardial iron removal in patients with transfusion-dependent anemias (CORDELIA) gave the opportunity to assess relative prevalence and body distribution of iron overload in screened patients.