Analysis of synovial fluid visfatin level in temporomandibular joint disorders

Yavuz G. Y., Kaya G., KIZILTUNÇ A.

CRANIO-THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE, cilt.37, sa.5, ss.296-303, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 5
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1080/08869634.2018.1429367
  • Dergi Adı: CRANIO-THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.296-303
  • Anahtar Kelimeler: Temporomandibular joint disorder, synovial fluid, biochemical analysis, adipokine, visfatin, COLONY-ENHANCING FACTOR, NECROSIS-FACTOR-ALPHA, INTERNAL DERANGEMENTS, RHEUMATOID-ARTHRITIS, ARTHROCENTESIS, INJECTION, PAIN, OSTEOARTHRITIS, INFLAMMATION, RECEPTOR
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Biochemical analysis of synovial fluid (SF) is an important means of understanding the pathogenesis of temporomandibular disorder (TMD) and confirming diagnoses made using traditional methods. Objective: The aim of this study was to determine whether or not SF visfatin levels can serve as a biochemical marker in the diagnosis of TMD. Method: Sixty samples of SF were obtained from 60 patients with internal derangement (ID) or osteoarthritis (OA). Visfatin in the SF was examined by enzyme-linked immunosorbent assay (ELISA). Result: Visfatin levels showed positive correlations with TMD pain and ID stage and a negative correlation with maximum mouth opening. In addition, Visfatin levels in joints with OA changes in the condyle were significantly higher in comparison to joints with no OA changes. Conclusion: Within the limitations of this study, it can be concluded that visfatin may play a role in the pathogenesis of TMD.