Changes in Tissue Substance P Levels in Patients With Carpal Tunnel Syndrome
NEUROSURGERY, vol.67, no.6, pp.1655-1660, 2010 (SCI-Expanded)
- Publication Type: Article / Article
- Volume: 67 Issue: 6
- Publication Date: 2010
- Doi Number: 10.1227/neu.0b013e3181fa7032
- Journal Name: NEUROSURGERY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1655-1660
- Keywords: Carpal tunnel syndrome, Immune, Neuron, Substance P, NEUROPATHIC PAIN, GENERAL-POPULATION, HISTAMINE-RELEASE, NERVE-FIBERS, CONSERVATIVE TREATMENT, ENDOTHELIAL-CELLS, CANAL PRESSURE, MESSENGER-RNA, MEDIAN NERVE, RAT
- Akdeniz University Affiliated: Yes
Abstract
BACKGROUND: Although carpal tunnel syndrome (CTS) is the most common entrapment neuropathy in adults, its etiology is not completely known. Chronic inflammation, fibrosis of the transverse carpal ligament (TCL), and altered sensory response contribute to the symptoms.