TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.31, sa.5, ss.1211-1217, 2011 (SCI-Expanded)
Objective: To investigate the association between abnormal one-hour 50-gram glucose challenge test and adverse perinatal outcome. Material and Methods: A retrospective study is performed in 212 patients screened for gestational diabetes between January 1999 and January 2005. Perinatal outcomes were compared between 123 patients with an abnormal glucose challenge test (blood glucose >= 140 gr with 50 gr glucose challenge test and normal with 100 gr oral glucose tolerance test) and 89 patients with normal 50 gr glucose challenge test. We used student t test, Mann-Whitney-U test, Chi square test for statistical evaluation. p< 0.05 is accepted as statistically significant. Results: There were no difference in demographic characteristics including age, gravidy, parity, and gestational week at the delivery between two groups. The patients with abnormal glucose challenge test results had maternal thyroid disease more frequently than control group (p = 0.02). Fetal macrosomia, antenatal death, shoulder dystocia, chorioamnionitis, preeclampsia, eclampsia, Cesarean delivery, postpartum endometritis, neonatal hypoglycemia, hypocalcemia, hyperbiluribinemia, and neonatal intensive care admission were comparable between two groups. Conclusion: Our data suggest that having an abnormal one-hour glucose challenge test is not an independent risk factor for an adverse perinatal outcome.