Acceleration of Distraction Osteogenesis With Drug-Releasing Distractor

KONAŞ E., MAVİLİ M. E., KORKUSUZ P., Demir D., Oner F., Canter H. I.

JOURNAL OF CRANIOFACIAL SURGERY, cilt.20, sa.6, ss.2041-2048, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 6
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1097/scs.0b013e3181be8754
  • Dergi Adı: JOURNAL OF CRANIOFACIAL SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2041-2048
  • Anahtar Kelimeler: Distraction osteogenesis, BMP, chitosan, controlled drug release, drug-releasing distractor, BONE MORPHOGENETIC PROTEIN-2, GRADUAL DISTRACTION, RABBIT MODEL, STERILIZATION, DELIVERY, RHBMP-2, RATES, OXIDE
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Objective: The aim of this study was to develop an internal distractor to release a drug to the distraction site during the distraction process and to investigate whether intermittent bone morphogenetic protein 2 (BMP-2)-containing chitosan hydrogel infusion will improve radiologic and histologic parameters of distraction osteogenesis (DO) when compared with control groups.