Protective effect of exendin-4 treatment on erectile dysfunction induced by chronic methylglyoxal administration in rats

Dalaklioglu, SELVİNAZ; TAŞATARGİL, ARDA; KUŞCU, NİLAY; ÇELİK, SONER; Celik-Ozenci, ÇİLER; ÖZDEM, SEBAHAT; Barutcigil, AYŞE; Kucukcetin, İKBAL

doi:10.1016/j.peptides.2018.05.005

Protective effect of exendin-4 treatment on erectile dysfunction induced by chronic methylglyoxal administration in rats

Dalaklioglu S., TAŞATARGİL A., KUŞCU N., ÇELİK S., Celik-Ozenci C., ÖZDEM S., ...More

PEPTIDES, vol.106, pp.1-8, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 106
Publication Date: 2018
Doi Number: 10.1016/j.peptides.2018.05.005
Journal Name: PEPTIDES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1-8
Keywords: MGO, Exendin-4, Corpus cavernosum, OXIDATION PROTEIN PRODUCTS, GLYCATION END-PRODUCTS, DIABETIC COMPLICATIONS, NITRIC-OXIDE, CORPUS CAVERNOSUM, RENAL-FAILURE, FREE-RADICALS, STRESS, MELLITUS, PATHWAY
Akdeniz University Affiliated: Yes

Abstract

Objective: The aim of this study was to investigate the effect of chronic exendin-4 (Ex-4) treatment on corpus cavernosum (CC) dysfunction in methylglyoxal (MGO) administered rats.