Association of circulating sTRAIL and high-sensitivity CRP with type 2 diabetic nephropathy and foot ulcers
MEDICAL SCIENCE MONITOR, cilt.19, ss.712-715, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 19
- Basım Tarihi: 2013
- Doi Numarası: 10.12659/msm.889514
- Dergi Adı: MEDICAL SCIENCE MONITOR
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.712-715
- Anahtar Kelimeler: soluble TRAIL, type-2 diabetes mellitus, diabetic nephropathy, diabetic foot, hsCRP, HbA1c, Wagner grading system, APOPTOSIS-INDUCING-LIGAND, METASTATIC COLON-CANCER, SOLUBLE TRAIL LEVELS, RECEPTOR, DEATH, DISEASE, ATHEROSCLEROSIS, OSTEOPROTEGERIN, RISK
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Akdeniz Üniversitesi Adresli: Evet
Özet
Background: Hyperglycemia is among the potent factors that may induce or facilitate apoptosis. TNF-Related Apoptosis-Inducing Factor (TRAIL) is known for its apoptotic and immunomodulatory effects that have recently been correlated with diabetes. We examined serum-soluble TRAIL (sTRAIL) and high-sensitivity CRP (hs-CRP) levels and their association with various distinct parameters in type 2 diabetic nephropathy patients with diabetic foot disease.