Ischemic Cerebral Infarction in an Infant Following Gonadotropin Treatment for Undescended Testes

DUNDAR N. O., Duman O., ARALASMAK A., HASPOLAT Ş.

JOURNAL OF CHILD NEUROLOGY, cilt.23, sa.11, ss.1324-1327, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 11
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1177/0883073808318057
  • Dergi Adı: JOURNAL OF CHILD NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1324-1327
  • Anahtar Kelimeler: cerebral infarction, gonadotropin, undescended testes, FACTOR-V-LEIDEN, RISK-FACTORS, STROKE, CHILDREN, PROTHROMBIN, AGE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Cerebrovascular disorders are increasingly recognized as important causes of mortality and morbidity in the pediatric population. Risk factors for stroke in childhood are different from those in adults. Human chorionic gonadotropin is a polypeptide hormone produced by the human placenta and is composed of an alpha-subunit and a beta-subunit. Pregnyl (human chorionic gonadotropin for injection) is a highly purified pyrogen-free preparation obtained from the urine of pregnatn females. Ischemic cerebral infarction is seen in the young infertile male and female patients after gonadotropin treatment. The authors describe the case of a boy with right-sided hemiparesis following Pregnyl injection and discuss its possible pathogenetic mechanisms.