The relation of radiation-induced pulmonary fibrosis with stress and the efficiency of antioxidant treatment: An experimental study
MEDICAL SCIENCE MONITOR, vol.20, pp.290-296, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 20
- Publication Date: 2014
- Doi Number: 10.12659/msm.890334
- Journal Name: MEDICAL SCIENCE MONITOR
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.290-296
- Keywords: Pulmonary Fibrosis, Oxidative Stress, Radiation, X, Vitamin E, Pentoxifylline, VITAMIN-E, OXIDATIVE STRESS, LUNG INJURY, PENTOXIFYLLINE, ADENOCARCINOMA, PNEUMONITIS, TOXICITY, PROTECTS, CASCADE, LIVER
- Open Archive Collection: AVESIS Open Access Collection
- Akdeniz University Affiliated: Yes
Abstract
Background: Radiation-Induced Lung Injury has 2 components: radiation pneumonitis and radiation fibrosis. The pulmonary fibrosis has no known efficient treatment. The purpose of this study was to study the relationship between the oxidant/antioxidant status and pulmonary fibrosis in rats having radiation induced pulmonary fibrosis and to study the antioxidant effects of pentoxifylline, vitamin E, and vitamin C in the treatment of pulmonary fibrosis.