The relation of radiation-induced pulmonary fibrosis with stress and the efficiency of antioxidant treatment: An experimental study

Creative Commons License

KAYA V., YAZKAN R., Yildirim M., KUMBUL DOĞUÇ D., Suren D., BOZKURT K. K., ...Daha Fazla

MEDICAL SCIENCE MONITOR, cilt.20, ss.290-296, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20
  • Basım Tarihi: 2014
  • Doi Numarası: 10.12659/msm.890334
  • Dergi Adı: MEDICAL SCIENCE MONITOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.290-296
  • Anahtar Kelimeler: Pulmonary Fibrosis, Oxidative Stress, Radiation, X, Vitamin E, Pentoxifylline, VITAMIN-E, OXIDATIVE STRESS, LUNG INJURY, PENTOXIFYLLINE, ADENOCARCINOMA, PNEUMONITIS, TOXICITY, PROTECTS, CASCADE, LIVER
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Radiation-Induced Lung Injury has 2 components: radiation pneumonitis and radiation fibrosis. The pulmonary fibrosis has no known efficient treatment. The purpose of this study was to study the relationship between the oxidant/antioxidant status and pulmonary fibrosis in rats having radiation induced pulmonary fibrosis and to study the antioxidant effects of pentoxifylline, vitamin E, and vitamin C in the treatment of pulmonary fibrosis.