Akademik Veri Yönetim Sistemi
Microchemical Journal, cilt.219, 2025 (SCI-Expanded, Scopus)
Here, oxidized multiwalled carbon nanotube (MWCNT)/Fe3O4 nanocomposite material was synthesized, characterized and applied in the magnetic solid phase micro-extractions of synthetic ADB-FUBINACA (Fubinaca) and 5F-AB-FUPPYCA (Fuppyca) cannabinoids from water samples. Optimization studies were performed to determine the optimum adsorption and desorption conditions of Fubinaca and Fuppyca in the extraction process via LC-MS/MS. New methods developed were used to quantify the trace amounts of synthetic Fubinaca and Fuppyca cannabinoids in tap water, synthetic wastewater, and simulated cleaning cloth washing water samples. Under the optimized conditions, the limit of detection and the limit of quantification values were determined to be 0.017 ng mL−1 and 0.035 ng mL−1 for Fubinaca and 0.056 ng mL−1 and 0.118 ng mL−1 for Fuppyca, respectively. New methods displayed good linearity in the concentration range of 1–25 ng mL−1, good precision (intra-day and inter-day relative standard deviations <4 %) and satisfactory recovery values in the range of 58.6–97.3 %. It was found that dust particles within the water sample affect negatively the recovery amounts of synthetic cannabinoids. The proposed methods were successfully used to analyze the Fubinaca and Fuppyca in various water samples. The results indicate that magnetic oxidized MWCNT/Fe3O4 nanoparticles can be used as an alternative material in the extraction of synthetic cannabinoids from water samples.