Association of Procalcitonin With Acute Pyelonephritis and Renal Scars in Pediatric UTI
PEDIATRICS, vol.131, no.5, pp.870-879, 2013 (SCI-Expanded)
- Publication Type: Article / Article
- Volume: 131 Issue: 5
- Publication Date: 2013
- Doi Number: 10.1542/peds.2012-2408
- Journal Name: PEDIATRICS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.870-879
- Keywords: acute pyelonephritis, children, procalcitonin, renal scarring, urinary tract infection, URINARY-TRACT-INFECTIONS, C-REACTIVE PROTEIN, SERUM PROCALCITONIN, FEBRILE INFANTS, PARENCHYMAL INVOLVEMENT, BACTERIAL-INFECTIONS, PUBLICATION BIAS, CHILDREN, PREDICTION, DIAGNOSIS
- Akdeniz University Affiliated: Yes
Abstract
BACKGROUND AND OBJECTIVE: Urinary tract infections (UTIs) are common childhood bacterial infections that may involve renal parenchymal infection (acute pyelonephritis [APN]) followed by late scarring. Prompt, high-quality diagnosis of APN and later identification of children with scarring are important for preventing future complications. Examination via dimercaptosuccinic acid scanning is the current clinical gold standard but is not routinely performed. A more accessible assay could therefore prove useful. Our goal was to study procalcitonin as a predictor for both APN and scarring in children with UTI.