Growth failure, tardive dyskinesia, megacolon development, and hepatic damage in neonatal rats following exposure to trimethobenzamide in utero

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Atıf İçin Kopyala

Erol A. Y., Gokcimen A., ÖZDEMİR O.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, cilt.24, sa.9, ss.1176-1180, 2011 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 24 Sayı: 9
• Basım Tarihi: 2011
• Doi Numarası: 10.3109/14767058.2010.536867
• Dergi Adı: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.1176-1180
• Anahtar Kelimeler: Trimethobenzamide, growth failure, tardive dyskinesia, megacolon, histopathology, liver, pregnancy, rat, TASTE-AVERSION, NAUSEA, REGENERATION
• Akdeniz Üniversitesi Adresli: Hayır

Özet

Objective. Trimethobenzamide (TMB) has a pregnancy category C labeling. Tardive dyskinesia and gastrointestinal involvement in neonates were not described earlier. We aimed to investigate neurological, developmental, and hepatic effects of TMB.