Intraperitoneal dedifferentiated liposarcoma: a case report.

Creative Commons License

Karaman A., Kabalar M., Ozcan O., Koca T., Binici D.

World journal of gastroenterology, vol.14, pp.5927-9, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14
  • Publication Date: 2008
  • Doi Number: 10.3748/wjg.14.5927
  • Journal Name: World journal of gastroenterology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.5927-9
  • Keywords: Dedifferentiated liposarcoma, p53 gene, Mutation, Intraperitoneum, SOFT-TISSUE SARCOMAS, P53 GENE, ESOPHAGEAL CANCERS, PROGNOSTIC FACTOR, MUTATIONS, GROWTH
  • Akdeniz University Affiliated: No

Abstract

Dedifferentiated liposarcoma is a variant of liposarcoma with a more aggressive course. Mutations of the p53 gene have been found in different types of soft tissue sarcoma. It is generally accepted that p53 mutations in human malignant tumors are often related to a poor prognosis. In our case, analysis of p53 gene mutation in tumor samples was performed. p53 gene mutation was observed in dedifferentiated tumor tissue samples but not in well-differentiated tumor tissue samples. It has been reported that p53 gene mutation occurs most commonly in the retroperitoneum and rarely in other anatomic locations. Herein we report a case of dedifferentiated liposarcoma located at intraperitoneum. (C) 2008 The WJG Press. All rights reserved.