Intraperitoneal dedifferentiated liposarcoma: a case report.

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Karaman A., Kabalar M., Ozcan O., Koca T., Binici D.

World journal of gastroenterology, cilt.14, ss.5927-9, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14
  • Basım Tarihi: 2008
  • Doi Numarası: 10.3748/wjg.14.5927
  • Dergi Adı: World journal of gastroenterology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5927-9
  • Anahtar Kelimeler: Dedifferentiated liposarcoma, p53 gene, Mutation, Intraperitoneum, SOFT-TISSUE SARCOMAS, P53 GENE, ESOPHAGEAL CANCERS, PROGNOSTIC FACTOR, MUTATIONS, GROWTH
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Dedifferentiated liposarcoma is a variant of liposarcoma with a more aggressive course. Mutations of the p53 gene have been found in different types of soft tissue sarcoma. It is generally accepted that p53 mutations in human malignant tumors are often related to a poor prognosis. In our case, analysis of p53 gene mutation in tumor samples was performed. p53 gene mutation was observed in dedifferentiated tumor tissue samples but not in well-differentiated tumor tissue samples. It has been reported that p53 gene mutation occurs most commonly in the retroperitoneum and rarely in other anatomic locations. Herein we report a case of dedifferentiated liposarcoma located at intraperitoneum. (C) 2008 The WJG Press. All rights reserved.