Akademik Veri Yönetim Sistemi
TURK ONKOLOJI DERGISI, cilt.40, sa.1, ss.11-19, 2025 (ESCI)
OBJECTIVE To evaluate the effect of volumetric changes in the bladder and rectum on clinical target volume (CTV) and organs at risk doses during adjuvant radiotherapy in gynecologic cancers. METHODS The study included 19 patients with gynecologic cancer who received adjuvant radiotherapy. Nineteen planning computed tomography scans and 171 megavoltage computed tomography (MVCT) scans were evaluated retrospectively. All structures were re-contoured on MVCT images using MIM software. The isodoses obtained from the reference plan were loaded onto the contoured MVCT images, and dosevolume histogram-based analysis was performed. RESULTS Analyses showed that patients with a bladder volume of ≥300 cc at the time of planning had lower bladder volumes (p=0.03) and higher mean bladder doses (p=0.04) during treatment compared with planning. Bladder volume deviation was found to be significantly higher in patients with a bladder volume of ≥300 cc at the time of planning (p=0.002). The mean treatment CTV V95% values of patients with planning bladder volumes of <150 cc, 150–300 cc, and ≥300 cc were 97.2%, 98.7%, and 98.9%, respectively (p=0.005). CONCLUSION Bladder and rectum filling have a critical impact on patients receiving adjuvant radiotherapy for gynecologic cancer. For optimal results, the bladder volume should be planned between 150 and 300 cc. Keywords: Adjuvant; bladder; filling; gynecologic cancer; radiotherapy; rectum. Copyright © 2025, Turkish Society for Radiation Oncology