Can we safely administer the recommended dose of phenobarbital in very low birth weight infants?

Öztekin O., Kalay S., Tezel G., Akcakus M., OYGÜR N.

CHILDS NERVOUS SYSTEM, cilt.29, sa.8, ss.1353-1357, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 8
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00381-013-2094-8
  • Dergi Adı: CHILDS NERVOUS SYSTEM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1353-1357
  • Anahtar Kelimeler: Very low birth weight infant, Seizure, Phenobarbital, NEONATAL SEIZURES TREATMENT, PHARMACOKINETICS, LEVETIRACETAM, VARIABILITY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

We investigated whether the recommended phenobarbital loading dose of 15-20 mg/kg with maintenance of 3-4 mg/kg/day can safely be administered to very low birth weight preterm newborns with seizures.