Türkiye Klinikleri Tıp Bilimleri Dergisi, cilt.39, sa.3, ss.263-270, 2019 (Scopus)
ABSTRACT Objective: The aim of this study is to compare dosimetric values of dynamic intensity modulated
radiation therapy (dIMRT) and volumetric modulated arc therapy (VMAT) treatment techniques in the treatment
of prostate cancer radiotherapy. Material and Methods: Treatment plans were designed for 10 high-risk
prostate cancer patient with Linac based 9-fields D-IMRT and double arc VMAT techniques using CMS
Monaco Treatment Planning System (TPS). Two planning techniques; were compared to homogeneity index
(HI) and conformity index (CI) values as well as the dose coverage of planning target volume (PTV) structures.
Critical organs were assessed V50, V60, V65, V70 for the rectum, V65, V70 for the bladder and V40
for the femoral heads. The treatment time, segment number and monitor unit (MU) values of the plans obtained
with the two techniques were compared. V37 was also evaluated as integral dose of the patients. All
obtained data were statistically evaluated by Wilcoxon signed rank test. Results: With the D-IMRT and
VMAT techniques, similar dose coverage were obtained for target volumes. HI and CI values calculated for
PTV 74 were found to be the similar in both techniques. With both planning techniques, all critical organs
could be kept below the dose limits. In general, in terms of organs at risk doses, close results were obtained
from both techniques. However, there was a significant difference between the two techniques in terms of
V70 values for rectum. A significant difference was also found between the two techniques in terms of integral
dose. Although the segment and MU numbers obtained from the plans generated by the VMAT technique
were higher than the plans generated by the D-IMRT technique, the treatment time was found shorter.
Conclusion: Similar dosimetric results were obtained from 9-fields D-IMRT and VMAT techniques used in
the treatment of prostate cancer radiotherapy in terms of PTV dose coverage and critical organ protection.
The VMAT technique has an advantage over the D-IMRT technique only in terms of treatment time.