Synergic and comparative effect of 5-fluorouracil and leucoverin on breast and colon cancer cells through TRPM2 channels
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.119, sa.11, ss.692-700, 2018 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 119 Sayı: 11
- Basım Tarihi: 2018
- Doi Numarası: 10.4149/bll_2018_124
- Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.692-700
- Anahtar Kelimeler: breast and colorectal cancers, TRPM2 channel, 5-flourouracil, leucoverin, oxidative stress, OXIDATIVE STRESS, CALCIUM OVERLOAD, APOPTOSIS, MELATONIN, MECHANISMS, TRPV1, CYTOTOXICITY, CHEMOTHERAPY, ACTIVATION
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Akdeniz Üniversitesi Adresli: Evet
Özet
OBJECTIVES: We aimed to reveal the role of 5-fluorouracil (5-FU) and Leucovorin (LV) along with transient receptor potential protein melastatin 2 (TRPM2) channels in breast and colon cancer cells during the treatment process.