PROLIFERATIVE EFFECTS OF METAMIZOLE SODIUM ON U-87 MG GLIOBLASTOMA CELL LINE: A PAIN KILLER OR A KILLER?


Kocak O., Simsek E.

WORLD CANCER RESEARCH JOURNAL, vol.8, 2021 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 8
  • Publication Date: 2021
  • Journal Name: WORLD CANCER RESEARCH JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Keywords: Metamizole Sodium, U-87 MG, Proliferation, Substance P, VEGF, Molecular Docking, SUBSTANCE-P, CANCER, RECEPTOR, DIPYRONE, DRUGS, ACTIVATION, MECHANISMS, MANAGEMENT, PATHWAYS, MORPHINE
  • Akdeniz University Affiliated: Yes

Abstract

Objective: During cancer treatment, painkillers are often used to alleviate patient pain. Metamizole is a pyrazolone derivative and a non-opioid pain reliever. Metamizole can be used alone in mild to moderate pain and can also be used with opioid group painkillers.