PROLIFERATIVE EFFECTS OF METAMIZOLE SODIUM ON U-87 MG GLIOBLASTOMA CELL LINE: A PAIN KILLER OR A KILLER?

Kocak O., Simsek E.

WORLD CANCER RESEARCH JOURNAL, cilt.8, 2021 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2021
  • Dergi Adı: WORLD CANCER RESEARCH JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Anahtar Kelimeler: Metamizole Sodium, U-87 MG, Proliferation, Substance P, VEGF, Molecular Docking, SUBSTANCE-P, CANCER, RECEPTOR, DIPYRONE, DRUGS, ACTIVATION, MECHANISMS, MANAGEMENT, PATHWAYS, MORPHINE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: During cancer treatment, painkillers are often used to alleviate patient pain. Metamizole is a pyrazolone derivative and a non-opioid pain reliever. Metamizole can be used alone in mild to moderate pain and can also be used with opioid group painkillers.