Mesenchymal stromal tumors of the stomach: Retrospective analysis of 9 patients


Arici C., Dincer D., Gurkan A., Dinckan A., Mesci A., Ogunc G.

CHIRURGISCHE GASTROENTEROLOGIE, vol.21, no.3, pp.285-288, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2005
  • Doi Number: 10.1159/000087090
  • Journal Name: CHIRURGISCHE GASTROENTEROLOGIE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.285-288
  • Keywords: gastrointestinal stromal tumor, stomach, mesenchymal tumor, GASTRIC LEIOMYOSARCOMA, SURGICAL-MANAGEMENT, WEDGE RESECTION
  • Akdeniz University Affiliated: No

Abstract

Background: Experiences with surgical therapy of stromal tumors of the stomach are presented. Material and Methods: We conducted a retrospective analysis of the medical and pathologic records of 9 patients who underwent surgical treatment for stromal tumor of the stomach between December 1998 and December 2003 at the Akdeniz University Medical Faculty Hospital. Results: Seven of the patients were women and 2 were men, with a median age of 62 (52 - 75) years. The most common presentation was weight loss and dyspepsia, followed by gastrointestinal bleeding and abdominal pain. Ultrasound and/or CT scan diagnosed the mass in gastric wall in all cases. Definitive preoperative diagnosis of GIST of the stomach was made in none of the patients. All patients underwent surgical resection; wedge resection with clear margins was done in 5 patients (splenectomy and distal pancreatectomy was additonally performed in 1 patient), distal gastrectomy in 3 patients, and total gastrectomy with splenectomy and partial hepatectomy in 1 patient. Regional lymph node dissection was generally restricted to adjacent lymph nodes. There was no postoperative death. Neither radiotherapy nor chemotherapy was given. Follow-up time ranged from 3 to 46 months (median 16 months). All patients, except 1, were alive without evidence of local and distant disease. One of the patients was re-operated for local recurrence 3 years after primary surgery. Conclusion: Complete resection of the stromal tumor of stomach with negative margins provides favorable outcome at least in short follow-up periods.

Background: Experiences with surgical therapy of stromal tumors of the stomach are presented. Material and Methods: We conducted a retrospective analysis of the medical and pathologic records of 9 patients who underwent surgical treatment for stromal tumor of the stomach between December 1998 and December 2003 at the Akdeniz University Medical Faculty Hospital. Results: Seven of the patients were women and 2 were men, with a median age of 62 (52 - 75) years. The most common presentation was weight loss and dyspepsia, followed by gastrointestinal bleeding and abdominal pain. Ultrasound and/or CT scan diagnosed the mass in gastric wall in all cases. Definitive preoperative diagnosis of GIST of the stomach was made in none of the patients. All patients underwent surgical resection; wedge resection with clear margins was done in 5 patients (splenectomy and distal pancreatectomy was additonally performed in 1 patient), distal gastrectomy in 3 patients, and total gastrectomy with splenectomy and partial hepatectomy in 1 patient. Regional lymph node dissection was generally restricted to adjacent lymph nodes. There was no postoperative death. Neither radiotherapy nor chemotherapy was given. Follow-up time ranged from 3 to 46 months (median 16 months). All patients, except 1, were alive without evidence of local and distant disease. One of the patients was re-operated for local recurrence 3 years after primary surgery. Conclusion: Complete resection of the stromal tumor of stomach with negative margins provides favorable outcome at least in short follow-up periods.