The effect of bilateral salpengectomy and tubal ligation on bone mass. Türkiye Klinikleri

ÇUBUKÇU FIRAT S., akar m., gökhan g., gürer e. i., üner m., trak b.

türkiye klinikleri jinekoloji ve obstetrik dergisi, vol.16, no.1, pp.6-11, 2006 (Peer-Reviewed Journal)

Abstract

Objective: To evaluate the effects of bilateral salpingectomy and tubal ligation on bone mass, in a rat model.
Material and Methods: Forty-eight female Wistar-albino rats weighing 200-250 g were divided equally into 3 groups underwent laparotomy, while no specific intervention was made to the 1. group. Bilateral tubal ligation by Pomeroy’s technique, bilateral salpingectomy was done to the 2. and 3. groups, respectively. Tissue samples taken from lumbar vertebrae and femoral neck were analysed to find out trabecular bone volume (TBV) in these study groups. TBVs were calculated according to the ratio of trabecular bone area to total bone area in X100 power field microscope area for each slide. Statistically, Kruskal-Wallis test was performed to analyse differences and correlations between groups.
Results: No statistical difference was found in TBV values of lumbar vertebra and femur neck in laporotomy, tubal ligation and salpingectomy groups (p= 0.119 for vertebrae, p= 0.625 for femur neck).
Conclusion: Our findings suggest that tubal ligation or salpingectomy does not have an increased short term risk for osteopenia.