Molecular Diagnosis for Nodal Metastasis in Endoscopically Managed Cervical Cancer: The Accuracy of the APTIMA Test to Detect High-risk Human Papillomavirus Messenger RNA in Sentinel Lymph Nodes

KOEHLER, Christhardt; LE, Xin; Dogan, NASUH; PFİFFER, Tatiana; Schneider, Achim; MARNITZ, Simone; BERTOLINI, Julia; favero, Giovanni

doi:10.1016/j.jmig.2016.03.003

Molecular Diagnosis for Nodal Metastasis in Endoscopically Managed Cervical Cancer: The Accuracy of the APTIMA Test to Detect High-risk Human Papillomavirus Messenger RNA in Sentinel Lymph Nodes

KOEHLER C., LE X., Dogan N. U., PFİFFER T., Schneider A., MARNITZ S., ...Daha Fazla

Journal of Minimally Invasive Gynecology, cilt.23, sa.5, ss.748-752, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 23 Sayı: 5
Basım Tarihi: 2016
Doi Numarası: 10.1016/j.jmig.2016.03.003
Dergi Adı: Journal of Minimally Invasive Gynecology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.748-752
Anahtar Kelimeler: Cervical cancer, Endoscopic sentinel node biopsy, Human papillomavirus messenger RNA, Molecular diagnostic, Nodal metastasis, FALSE-NEGATIVE RATE, CARCINOMA, DNA, RECURRENCE, BIOPSY, TUMOR, PCR
Akdeniz Üniversitesi Adresli: Evet

Özet

Study Objective: To evaluate the feasibility and accuracy of a commercially available test to detect E6/E7 mRNA of 14 subtypes of high-risk HPVs (APTIMA; Hologic, Bedford, MA) in the sentinel lymph nodes of CC patients laparoscopically operated.