Perceived stress and hair cortisol: Differences in bipolar disorder and schizophrenia

Streit F., Memic A., Hasandedic L., Rietschel L., Frank J., Lang M., ...Daha Fazla

PSYCHONEUROENDOCRINOLOGY, cilt.69, ss.26-34, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.psyneuen.2016.03.010
  • Dergi Adı: PSYCHONEUROENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.26-34
  • Anahtar Kelimeler: Bipolar disorder, Schizophrenia, Hair cortisol, Perceived stress, Genetic risk, PITUITARY-ADRENAL AXIS, LIFE EVENTS, PSYCHOSOCIAL STRESS, HPA AXIS, HIGH-RISK, SOCIAL STRESS, 1ST EPISODE, INDIVIDUALS, RESPONSES, METAANALYSIS
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Introduction: Bipolar disorder (BD) and schizophrenia (SCZ) are psychiatric disorders with shared and distinct clinical and genetic features. In both disorders, stress increases the risk for onset or relapse and dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis has been reported. The latter is frequently investigated by measuring changes in the hormonal end product of the HPA axis, i.e., the glucocorticoid cortisol, whose concentration exhibits diurnal variation. The analysis of hair cortisol concentration (HCC) is a new method, which allows assessment of cumulative cortisol secretion over the preceding three months.