Can Mean Platelet Volume be a New Risk Factor in Portal Venous Thrombosis?
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, vol.19, no.4, pp.433-436, 2013 (SCI-Expanded)
- Publication Type: Article / Article
- Volume: 19 Issue: 4
- Publication Date: 2013
- Doi Number: 10.1177/1076029612464903
- Journal Name: CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.433-436
- Keywords: portal venous thrombosis, mean platelet volume, etiology, VEIN-THROMBOSIS, ACTIVATION
- Akdeniz University Affiliated: No
Abstract
Background: The aim of this study was to discuss the possibility of mean platelet volume (MPV) being a new risk factor in the etiology of portal venous thrombosis (PVT). Methods: Study participants were categorized into 2 different groups: group I, control group (n = 35) and group II, PVT group (n = 34). Demographic data and MPV values were recorded retrospectively. Results: No differences were determined between the 2 groups regarding hypertension, diabetes mellitus, and smoking (P > .05). The average hemoglobin levels were 10.8 +/- 2.1 in group II and 14.0 +/- 1.7 in group I (P < .001). Although the MPV levels of group II patients were 8.2 +/- 0.52, the average level in group I was determined as 7.8 +/- 0.62 (P = .012). In the performed receiver-operating characteristic (ROC) analysis, the cutoff value for patients with PVT for MPV was determined as 7.9 (area under curve: 0.674), sensitivity as 70.6%, and specificity as 65.7% (P = .013). Conclusion: The current study shows that MPV is significantly higher in patients with PVT than in the control group.