Boric acid inhibits alveolar bone loss in rats by affecting RANKL and osteoprotegerin expression

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Saglam M., HATİPOĞLU M., Koseoglu S., Esen H. H., Kelebek S.

JOURNAL OF PERIODONTAL RESEARCH, vol.49, no.4, pp.472-479, 2014 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 49 Issue: 4
• Publication Date: 2014
• Doi Number: 10.1111/jre.12126
• Journal Name: JOURNAL OF PERIODONTAL RESEARCH
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.472-479
• Keywords: alveolar bone loss, boric acid, osteoprotegerin, periodontal diseases, receptor activator of nuclear factor-kappa B ligand, EXPERIMENTAL PERIODONTITIS, DIETARY BORON, RECEPTOR ACTIVATOR, SUPPLEMENTATION, NUTRITION, DISEASE
• Akdeniz University Affiliated: Yes

Abstract

Background and Objective: The goal of the present study was to evaluate the effects of systemic boric acid on the levels of expression of RANKL and osteoprotegerin (OPG) and on histopathologic and histometric changes in a rat periodontitis model.