Expression patterns of claudins 1, 4, and 7 and their prognostic significance in nasopharyngeal carcinoma

Suren D., Yildirim M., KAYA V., Elal R., Selcuk O. T., Osma U., ...More

JOURNAL OF BUON, vol.20, no.1, pp.212-217, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2015
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.212-217
  • Keywords: Claudin 1, Claudin 4, Claudin 7, nasopharyngeal cancer, prognosis, tight junctions, SQUAMOUS-CELL CARCINOMA, REDUCED EXPRESSION, TIGHT, CANCER, PROTEINS, INVASION
  • Akdeniz University Affiliated: Yes

Abstract

Purpose: Tight junction (TJ) proteins in the cells organize paracellular permeability, and they have a critical role in apical cell-to-cell adhesion and epithelial polarity. In our study, the expression patterns of claudins 1, 4, and 7 and their relationship with prognosis were determined in patients with nasopharyngeal carcinoma.