Expression patterns of claudins 1, 4, and 7 and their prognostic significance in nasopharyngeal carcinoma

Suren, Dinc; Yildirim, MUSTAFA; KAYA, Vildan; Elal, Ruksan; Selcuk, Omer; Osma, ÜSTÜN; Yildiz, Mustafa; Gunduz, ŞEYDA; Sezer, Cem

Expression patterns of claudins 1, 4, and 7 and their prognostic significance in nasopharyngeal carcinoma

Suren D., Yildirim M., KAYA V., Elal R., Selcuk O. T., Osma U., ...Daha Fazla

JOURNAL OF BUON, cilt.20, sa.1, ss.212-217, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 1
Basım Tarihi: 2015
Dergi Adı: JOURNAL OF BUON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.212-217
Anahtar Kelimeler: Claudin 1, Claudin 4, Claudin 7, nasopharyngeal cancer, prognosis, tight junctions, SQUAMOUS-CELL CARCINOMA, REDUCED EXPRESSION, TIGHT, CANCER, PROTEINS, INVASION
Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: Tight junction (TJ) proteins in the cells organize paracellular permeability, and they have a critical role in apical cell-to-cell adhesion and epithelial polarity. In our study, the expression patterns of claudins 1, 4, and 7 and their relationship with prognosis were determined in patients with nasopharyngeal carcinoma.