CLOCK Gene Variants Associate with Sleep Duration in Two Independent Populations

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Allebrandt K. V., Teder-Laving M., Akyol M., Pichler I., Mueller-Myhsok B., Pramstaller P., ...More

BIOLOGICAL PSYCHIATRY, vol.67, no.11, pp.1040-1047, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 11
  • Publication Date: 2010
  • Doi Number: 10.1016/j.biopsych.2009.12.026
  • Journal Name: BIOLOGICAL PSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1040-1047
  • Keywords: CLOCK, sleep duration, clock genes, MCTQ, short sleepers, long sleepers, CIRCADIAN CLOCKS, TRANSCRIPTION FACTOR, POLYMORPHISM, SUSCEPTIBILITY, ADOLESCENTS, HOMEOSTASIS, DISSECTION, PREFERENCE, REGULATOR, MOUSE
  • Akdeniz University Affiliated: Yes

Abstract

Background: Sleep is an active and complex behavior, yet it has two straightforward properties-timing and duration. Clock genes are associated with dysfunctional timing of sleep, mood, and obesity disorders, which are commonly associated with sleep duration.