Early Changes in Carcinogenesis of Colorectal Adenomas

TORU H. S., Bilezikci B.

WEST INDIAN MEDICAL JOURNAL, cilt.61, sa.1, ss.10-16, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.7727/wimj.2011.136
  • Dergi Adı: WEST INDIAN MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.10-16
  • Anahtar Kelimeler: Adenomatous polyps, carcinogenesis, HPV, HUMAN-PAPILLOMAVIRUS INFECTION, COLON-CANCER, CYCLIN D1, GENE-MUTATIONS, E-CADHERIN, EXPRESSION, CARCINOMA, P53, BCL-2, HPV
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objectives: Adenocarcinoma of the colon and rectum is the third most common cause of cancer deaths and the sixth most common cancer in the world. Adenomas are benign neoplastic lesions which can be transformed into carcinomas, but this is usually not the case. There should be some risk factors which lead to the development of carcinomas into adenomas. The aim of this study is to find out the early changes and high risk factors related to carcinogenesis in colonic polyps.