Immunomodulatory, hemolytic and cytotoxic activity potentials of triterpenoid saponins from eight Cephalaria species

SARIKAHYA N., NALBANTSOY A., Top H., GÖKTÜRK R. S., SÜMBÜL H., Kirmizigul S.

PHYTOMEDICINE, cilt.38, ss.135-144, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.phymed.2017.11.009
  • Dergi Adı: PHYTOMEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.135-144
  • Anahtar Kelimeler: Cytotoxic activity, Hemolytic activity, Immunomodulatory activity, Cephalaria, Caprifoliaceae, Triterpene saponin, AERIAL PARTS, CANCER-CELLS, IN-VITRO, GLYCOSIDES, IDENTIFICATION, ADJUVANTS, IMMUNITY, ROOTS, CHINENSIS, MEMBRANES
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Saponins isolated from a number of plants possess a broad spectrum of biological and pharmacological activities by using in vitro and in vivo bioassays. The recent investigations and findings in biological activity studies of saponins have mostly focused on immunomodulatory, hemolytic and cytotoxic properties.