Factor V Deficiency Associated with Congenital Cardiac Disorder and Intracranial Hemorrage

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Ozkaya H., Akcan A. B., Aydemir G., Akcan M., Kul M.

INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION, cilt.29, sa.2, ss.99-101, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s12288-012-0149-8
  • Dergi Adı: INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.99-101
  • Anahtar Kelimeler: Factor V deficiency, Intracranial hemorrage, Bleeding disorder, HEMORRHAGE, GENE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Factor V deficiency is an inherited disorder, in which the clotting factor V is low. The disorder is very rare, occurring in only one in one million people. It is inherited as an autosomal recessive disorder. The results of coagulation studies include a prolonged prothrombin time and partial thromboplastin time associated with reduced plasma factor V content. Patients with factor V deficiency have a hemophiliac like hemorrhagic disorder. Epistaxis, bruising, and menorrhagia are some of the common features. If treatment is needed, fresh frozen plasma is typically given. In this report we present a 12 year old girl who was admitted to our clinic with recurrent nosebleeds and intracranial hemorrage after head trauma. After examination, factor V deficiency was diagnosed. She also had congenital cardiac disorder (VSD), probably a co-incidental finding.