Expression of cyclooxygenase-2 and Bcl-2 in breast cancer and their relationship with triple-negative disease

Alikanoglu A. S., Yildirim M., Suren D., Yildiz M., KAYA V., Dilli U. D., ...More

JOURNAL OF BUON, vol.19, no.2, pp.430-434, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 2
  • Publication Date: 2014
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.430-434
  • Keywords: Bcl-2, breast cancer, COX-2, triple negative, PROGNOSTIC-SIGNIFICANCE, GASTRIC-CARCINOMA, APOPTOSIS, P53, OVEREXPRESSION, INHIBITORS, FEATURES, BIOLOGY, PROTEIN, COX-2
  • Akdeniz University Affiliated: Yes

Abstract

Purpose: Carcinogenesis is a multistep process with many factors being involved. The aim of this study was to investigate the role of cyclooxygenase-2 (COX-2) and Bcl-2 expression in patients with triple-negative breast cancer (TNBC) and, also whether any differences exist between TNBC and non-TNBC patients in relation with these two parameters.