Expression of cyclooxygenase-2 and Bcl-2 in breast cancer and their relationship with triple-negative disease


Alikanoglu A. S., Yildirim M., Suren D., Yildiz M., KAYA V., Dilli U. D., ...Daha Fazla

JOURNAL OF BUON, cilt.19, sa.2, ss.430-434, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 2
  • Basım Tarihi: 2014
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.430-434
  • Anahtar Kelimeler: Bcl-2, breast cancer, COX-2, triple negative, PROGNOSTIC-SIGNIFICANCE, GASTRIC-CARCINOMA, APOPTOSIS, P53, OVEREXPRESSION, INHIBITORS, FEATURES, BIOLOGY, PROTEIN, COX-2
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: Carcinogenesis is a multistep process with many factors being involved. The aim of this study was to investigate the role of cyclooxygenase-2 (COX-2) and Bcl-2 expression in patients with triple-negative breast cancer (TNBC) and, also whether any differences exist between TNBC and non-TNBC patients in relation with these two parameters.