Decreased serum levels of brain-derived neurotrophic factor in schizophrenic patients with deficit syndrome


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akyol E. S., albayrak Y., beyazyüz M., aksoy N., Kuloglu M. M., Hashimoto K.

NEUROPSYCHIATRIC DISEASE AND TREATMENT, vol.11, pp.865-872, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11
  • Publication Date: 2015
  • Doi Number: 10.2147/ndt.s79444
  • Journal Name: NEUROPSYCHIATRIC DISEASE AND TREATMENT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.865-872
  • Keywords: biomarker, neurotrophin, psychosis, BDNF LEVELS, ATYPICAL ANTIPSYCHOTICS, TARDIVE-DYSKINESIA, BIPOLAR DISORDER, DISEASE, PLASMA, METALLOPROTEINASES, POTENTIATION, MODULATION, DEPRESSION
  • Akdeniz University Affiliated: Yes

Abstract

Background: Brain-derived neurotrophic factor (BDNF) is a well-established neurotrophin that plays a role in the pathophysiology of numerous psychiatric disorders. Many studies have investigated the serum BDNF levels in patients with schizophrenia. However, there are restricted data in the literature that compare the serum BDNF levels in patients with deficit and nondeficit syndromes. In this study, we aimed to compare the serum BDNF levels between schizophrenic patients with deficit or nondeficit syndrome and healthy controls.