Decreased serum levels of brain-derived neurotrophic factor in schizophrenic patients with deficit syndrome

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akyol E. S., albayrak Y., beyazyüz M., aksoy N., Kuloglu M. M., Hashimoto K.

NEUROPSYCHIATRIC DISEASE AND TREATMENT, cilt.11, ss.865-872, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11
  • Basım Tarihi: 2015
  • Doi Numarası: 10.2147/ndt.s79444
  • Dergi Adı: NEUROPSYCHIATRIC DISEASE AND TREATMENT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.865-872
  • Anahtar Kelimeler: biomarker, neurotrophin, psychosis, BDNF LEVELS, ATYPICAL ANTIPSYCHOTICS, TARDIVE-DYSKINESIA, BIPOLAR DISORDER, DISEASE, PLASMA, METALLOPROTEINASES, POTENTIATION, MODULATION, DEPRESSION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Brain-derived neurotrophic factor (BDNF) is a well-established neurotrophin that plays a role in the pathophysiology of numerous psychiatric disorders. Many studies have investigated the serum BDNF levels in patients with schizophrenia. However, there are restricted data in the literature that compare the serum BDNF levels in patients with deficit and nondeficit syndromes. In this study, we aimed to compare the serum BDNF levels between schizophrenic patients with deficit or nondeficit syndrome and healthy controls.