Turkish Journal of Biochemistry, 2025 (SCI-Expanded)
This systematic review aims to identify common preanalytical errors in pediatric blood sampling. A literature search was conducted in PubMed, Web of Science, and EBSCOhost databases, with March 23, 2024 being the cut-off point. The search was conducted with a variety of keywords, such as 'preanalytical errors,' 'blood sampling,' 'child,' 'neonatal,' and 'infant', along with 'AND/OR' operators. Two researchers independently assessed the quality of the included studies, and the data from the selected studies were presented in tables. Nine studies published in English were included in this review, comprising seven descriptive studies and two case reports, involving involved a total of 110,120 pediatric blood samples. Most studies did not use a specific data collection tool; instead, they performed blood analyses using tubes. The most common preanalytical errors identified were inappropriate blood volumes in tubes, non-compliance with blood collection procedures, sample clotting, use of incorrect tubes, and contamination. According to the results of this systematic review, systematic theoretical and practical training programs should be implemented, phlebotomy practices should be periodically audited, and quality indicators should be continuously monitored to prevent preanalytical errors in pediatric blood sampling.